Diffusion and phase change characterization by mass Spectrometry

  • 105 Pages
  • 3.70 MB
  • English
National Aeronautics and Space Administration, Scientific and Technical Information Branch, For sale by the National Technical Information Service] , Washington, D.C, [Springfield, Va
StatementMark E. Koslin and Frederick A. White ; prepared for Langley Research Center under grant NSG-1360.
SeriesNASA contractor report -- 3165., NASA contractor report -- NASA CR-3165.
ContributionsWhite, Frederick Andrew, 1918-, United States. National Aeronautics and Space Administration. Scientific and Technical Information Branch., Langley Research Center.
The Physical Object
Paginationvi, [105] p. :
ID Numbers
Open LibraryOL17653415M

Diffusion and Phase Change Characterization by Mass Spectrometry Mark E. Koslin and Frederick A. White Rensselaer Polytechnic Institute Troy, New York Prepared for Langley Research Center under Grant NSG- National Aeronautics and Space Administration Scientific File Size: 4MB.

Diffusion and phase change characterization by mass spectrometry. Washington, D.C.: National Aeronautics and Space Administration, Scientific and Technical Information Branch; [Springfield, Va.: For sale by the National Technical Information Service], (OCoLC) Material Type: Government publication, Diffusion and phase change characterization by mass Spectrometry book government publication.

Characterization of Impurities and Degradants Using Mass Spectrometry examines how mass spectrometry (MS) can be applied to improve the drug development process and get drugs approved more quickly.

This book looks at spectrometry with an overview of its capabilities, and then guides the reader on techniques as they relate to the analysis of impurities and degradants, showing why these Format: Hardcover.

Diffusion and phase change characterization by mass spectrometry. By M. Koslin and F. White. Abstract. The high temperature diffusion of trace elements in metals and alloys was investigated. Measurements were made by high sensitivity mass spectrometry in which individual atoms were detected, and quantitative data was obtained for Author: M.

Koslin and F. White. Diffusion and phase change characterization by mass spectrometry / (Washington, D.C.: National Aeronautics and Space Administration, Scientific and Technical Information Branch; [Springfield, Va.: For sale by the National Technical Information Service], ), by Mark E.

Koslin, Frederick Andrew White, Langley Research Center, and United States. Mass Spectrometry: Principles and Applications, Third Edition. Edmond de Hoffmann, Université Catholique de Louvain, Belgium and Vincent Stroobant, Ludwig Institute for Cancer Research, Brussels Branch, Belgium.

Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass by:   This study describes a novel approach for monitoring noncovalent interactions in solution by electrospray mass spectrometry (ESI-MS).

The technique is based on measurements of analyte diffusion in solution. Diffusion coefficients of a target macromolecule and a potential low molecular weight binding partner are determined by measuring the spread of an initially sharp boundary between Cited by: In this work, thermal and phase stability of primary CoSb 3 skutterudite prepared by different procedures were investigated using thermal analysis and Knudsen effusion mass spectrometry performed on a Netzsch STA CD/3//5/G apparatus, a specially-adapted type of the commercial STA CD - QMS /5 Skimmer Coupling Instrument.

Results Author: Nathan Jacobson, Dietmar Kobertz, Dmitry Sergeev.

Details Diffusion and phase change characterization by mass Spectrometry PDF

This two-volume book provides an overview of physical techniques used to characterize the structure of solid materials, on the one hand, and to investigate the reactivity of their surface, on the other.

Therefore this book is a must-have for anyone working in fields related to surface reactivity. Mass spectrometry has been applied to identify and structurally elucidate AGEs.

Here, we report on the identification of AGE- peptides and AGE-precursors based on relative mass changes as a result. Advances in mass spectrometry.

Mass spectrometers continue to evolve, propelled by demands from the proteomics community for increased sensitivity, higher mass accuracy and resolving power, improved duty cycle and more efficient fragmentation of peptides in MS/MS.

Electrospray ionisation MS/MS has been used for several years for peptide by: Mass spectrometry 1. Solubilize digested peptide samples into a working volume of HPLC grade 5% acetonitrile/% formic acid for injection into the HPLC autosampler, typically µl volumes are reasonable.

Resulting peptides are injected onto a 3-µm C 18 reversed-phase (RP) resin column (Acclaim PepMap, 75 µm × 15 cm). In this work, reversed-phase liquid chromatography and mass spectrometry were used to characterize four of the most abundant thiol modifiers on recombinant proteins secreted from E.

coli BL21 (DE3. Tandem Mass Spectrometry Molecular Characterization. This book serves multiple groups of audiences; professional, graduate students and general readers interested in the use of modern mass spectrometry in solving critical questions of chemical and biological sciences.

The areas covered include the analysis of drugs, metabolites, carbohydrates. Chelius D, Huff Wimer ME, Bondarenko PV (a) Reversed-phase liquid chromatography in-line with negative ionization electrospray mass spectrometry for the characterization of the disulfide-linkages of an immunoglobulin gamma antibody.

J Am Soc Mass Cited by: 3. Trypsin: Mass Spectrometry Sample Preparation OVERVIEW Figure The high quality of Promega trypsin is achieved by chemical modification, affinity purification and strict lot-release criteria.

Trypsin Gold, Mass Spectrometry Grade (Cat.# V) is mass spectrometry-qualified. Protein Characterization 7 by Mass Spectrometry.

A sodium acetate trihydrate (SAT)-urea binary eutectic mixture was developed as a phase change material (PCM). Using the differential scanning calorimetry (DSC) experiment and synthetic visual method, the solid–liquid phase diagram of SAT-urea was obtained, through which the eutectic composition of SAT-urea binary mixture was determined.

The results show that the binary eutectic. Tandem Mass Spectrometry - Molecular Characterization presents a comprehensive coverage of theory, instrumentation and description of experimental strategies and MS/MS data interpretation for the structural characterization of relevant molecular compounds.

The areas covered include the analysis of drugs, metabolites, carbohydrates and protein post-translational modifications. The book series Cited by: 5. AbstractThe described approach allows the determination of homopolymer characteristics from complex electrospray mass spectra of multicharged ions in the range of to It makes mass spectrometric characterizations possible where compounds are fragmented under MALDI conditions.

The determination is accomplished by simulation of the observed complex mass spectra Cited by: 2. Mass spectrometry 1. Mass spectrometry (MS) By: Dr. Ashish C Patel, Assistant Professor, Animal Genetics & Breeding, Veterinary College, Anand 2.

Mass spectrometry (MS) • Mass spectrometry (MS) measures the mass-to-charge ratio of ions to identify and quantify molecules in simple and complex mixtures. Mass spectrometry data is provided for each mass up to amu.

Description Diffusion and phase change characterization by mass Spectrometry FB2

Masses of 18, 32 and 44 are especially important, corresponding to water, oxygen and carbon dioxide, respectively. It is especially important to note that no significant, larger mass peaks are detected during the major weight loss event in any of the by: 6. (butadiene)-styrene based copolymers by mass spectrometry and their impact on the car-indoor environment``, Slovak University of Technology, Chemické listy, Vol.pISSN Direct Inlet – Electron Impact – Mass Spectrometry.

Electrospray ionization mass spectrometry is a soft ioniza- tion technique that has been widely used in the biological arena. ES1 is a method for transforming ions that are pre- sent in solution into the gas phase for mass spectral analy- sis. A sample solution is sprayed or nebulized under the.

bombardment was needed to sustain growth of the α phase. Energy-resolved mass spectrometry measurements demonstrate that the likely source of energetic bombardment, in the present case, was oxygen ions/atoms originating from the target surface.

Overall, these results demonstrate that low-temperature α-alumina growth is possible by controlling File Size: KB. The main aim of diabetic nephropathy monitoring is to identify molecular markers, that is, to find changes occurring at metabolome and proteome levels indicative of the disease's development.

The mass spectrometry methods available today have been successfully applied to this field. This paper provides a short description of the basic aspects Cited by: 3. While mass spectrometry has emerged as the gold standard, it is not the only means available for the structural characterization of mAbs.

In liquid chromatography, orthogonal separations methods have been made more powerful by improved first-to-second dimension interfaces that preserve first-dimension separations at high resolution and allow Author: Matthew Wygant.

• Characterization of proteins and peptides involves three different processes: • Dissociation of matrix, phase change to super‐compressed gas, • Can perform multiple stages of mass spectrometry without additional mass analyzers.

• Have a wide mass range and excellentFile Size: 2MB. 4.

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DEFINITION: Mass spectrometry (MS) is an analytical chemistry technique that helps identify the amount and type of chemicals present in a sample by measuring the mass- to-charge ratio and abundance of gas-phase ions.

PRINCIPLE: A mass spectrometer generates multiple ions from the sample under investigation This molecular ion undergoes. A method is presented for the chemical characterization of natural organic matter (NOM).

We combined reversed-phase chromatographic separation of NOM with high resolution inductively coupled plasma mass spectrometry. A desolvation technique was used to remove organic solvent derived from the preceding chromatographic separation.

We applied our method to solid-phase extracted marine Cited by:   Doping is indispensable to tailor phase-change materials (PCM) in optical and electronic data storage. Very few experimental studies, however, have provided quantitative information on the Cited by: 8.

Recent successes illustrate the role of mass spectrometry-based proteomics as an indispensable tool for molecular and cellular biology and for the emerging field of Cited by: Phase-change processes produce a solid part from liquid material. They include the commercial processes of metal casting, infiltration of composites, and injection molding of polymers.

These processes may reside early in the process stream (e.g., ingot casting of wrought metallic products) or produce a finished component (e.g., a molded. An isotopic signature (also isotopic fingerprint) is a ratio of non-radiogenic 'stable isotopes', stable radiogenic isotopes, or unstable radioactive isotopes of particular elements in an investigated material.

The ratios of isotopes in a sample material are measured by isotope-ratio mass spectrometry against an isotopic reference process is called isotope analysis.